BeyondTinnitus Clinical & Scientific Information

BeyondTinnitus® is established on foundation of previously done or ongoing clinical studies, and has been designed based on several years of research and experience with tinnitus patients. Please click below to the right for the studies.

Accuracy of Tinnitus Frequency Matching Using a Web-Based Protocol

Accuracy of Tinnitus Frequency Matching Using a Web-Based Protocol (Abstract presented at the American Academy of Otolaryngology-Head and Neck Surgery meeting, San Francisco, CA, September 2011. Paper accepted at European Archives of Otolaryngology).

Objective: To investigate the accuracy of a web-based protocol for tinnitus frequency matching in comparison to audiometry

Patients:  Subjects who suffered from subjective tinnitus were enrolled.

Intervention(s): Twenty subjects had tinnitus frequency matching in a random order using an audiometer in an anechoic chamber and using a web-based software with a multiple-choice protocol and a slider. Octave challenge testing was performed.

Main Outcome Measure(s): The results of the tinnitus frequency matching between different protocols were compared. Participants were asked to indicate that which protocol resulted in the closest match to their tinnitus frequency.

Results: Median tinnitus frequency was 6000Hz (range, 2000-12000Hz) using the audiometer and self-directed multiple-choice protocol. Using the slider, the median frequency was 5925Hz (range, 1850-16000Hz). The patients with tinnitus frequency of over 12000Hz experienced a higher level of satisfaction when using the computer-based slider system. Five patients experienced octave confusion with self-directed multiple-choice tinnitus matching that was corrected accurately after the octave challenge step.

Conclusions: A web-based protocol for tinnitus frequency matching is as accurate as a standard audiometric protocol. An octave challenge test is necessary for a patient-directed tinnitus frequency matching.

Customized Web-Based Sound Therapy for Tinnitus

Customized Web-Based Sound Therapy for Tinnitus (Presented at the American Academy of Otolaryngology-Head and Neck Surgery meeting, San Francisco, CA, September 2011. Paper accepted in Annals of Otology, Rhinology, and Laryngology).

Introduction: Traditional masking efforts have presented broadband noises, most typically white noise. Targeted (customized) sound therapies have been introduced to overcome the limitations of traditional maskers.

Objectives: To evaluate the efficacy of a web-based delivery of customized sound therapy in reducing tinnitus loudness and increasing the residual inhibition.

Materials and Methods: Thirty-two subjects matched their tinnitus frequency using a web-based protocol. A customized Harmonic Sound Therapy file was produced by the web-based software and downloaded by the patient onto an MP3 player. The subjects listened to the sound file for one hour.

Results: Tinnitus loudness mean was 6.0 ± 2.3 standard deviation (SD) which decreased to 3.3 ± 1.9 SD after one hour of sound therapy. Some reduction in loudness was seen in 81%, while 72% experienced a reduction of 25% or more. Tinnitus annoyance decreased from an average of 6.1 ± 2.6 SD to 3.1 ± 2.0 SD. Median duration of residual inhibition was 32.5 minutes, with an average of 75 minutes ± 132 SD.

Conclusion: Customized sound therapy can be delivered via the internet. Harmonic Sound Therapy is effective in reducing the loudness and annoyance of tinnitus.

Telemedicine Approach to Tinnitus Treatment: Customized Harmonic Sound and Music Therapy

Telemedicine Approach to Tinnitus Treatment: Customized Harmonic Sound and Music Therapy (Abstract presented at the International State-of-the-Science meeting on Blast-induced Tinnitus, Chantilly, VA, November 2011. Paper accepted at the International Tinnitus Journal).

Background: We have developed a validated web-based software that is capable of identifying the tinnitus frequency, loudness, and interaural difference of tinnitus. In addition, we have developed harmonic sound therapy, a patent-pending sound therapy protocol which has been found to be effective in temporarily reducing the perception of tinnitus when used short term. The patient is able to access the site, find his/her tinnitus and based on the characteristics of the tinnitus, a customized sound therapy file can be delivered to the patient via the web. The patient is able to use the web-based software to mix their own music with the sound therapy file. This allows the patient to listen to their own music while the therapy sound is working in the background. The objective of this study was to evaluate the efficacy of a customized harmonic sound and music therapy using a web-based protocol in the treatment of tinnitus.

 Methods: Twenty-eight patients with tinnitus (minimum duration of 6 months), were enrolled in the study. The therapy consisted of 2 stages: In the sound therapy stage, the subjects listen to the customized harmonic sound therapy file on a commercial MP3 player for 2 weeks for a minimum of 2 hours per day using open ear headphones. The second stage involves listening to a mixture of the harmonic sound therapy with music for a minimum of 2 hours a day for the next 5.5 months.  Outcomes were assessed using a VAS for loudness and annoyance as well as the Tinnitus Handicap Inventory (THI).

 Results: Overall, 24 of the 28 patients (89%) showed a significant improvement in loudness, annoyance, and THI. The mean reduction of tinnitus loudness changed from an average of 6.7 to 3.4 on a scale of 0 to 10. Tinnitus annoyance showed a reduction of 52% on the average (range, 0 to 89%). THI score was reduced in 75% of patients by at least 30%. In the entire cohort, the mean difference in THI was 20 (range -2 to 52).

 Conclusion: Customized harmonic sound and music therapy is an effective method of tinnitus treatment in patients with tinnitus. The software that has been developed will allow this treatment to be delivered in a telemedicine approach via the web to anywhere in the world. This treatment is suited for forward field applications as well as for veterans located in remote parts of the U.S. or world. An audiologist based in a medical center can help a service member in the field or in a remote location with delivery of customized sound therapy over the web. The servicemember or veteran can also use their own music to develop customized music therapy files using the web-based protocol. The use of open-ear headphones allows for the user to hear outside sounds while listening to therapy sounds.